SYSTEMIC REGULATION OF RETINAL MEDIUM-CHAIN FATTY ACID OXIDATION REPLETES TCA CYCLE FLUX IN OXYGEN-INDUCED RETINOPATHY

Systemic regulation of retinal medium-chain fatty acid oxidation repletes TCA cycle flux in oxygen-induced retinopathy

Abstract Activation of anaplerosis takes away glutamine from the biosynthetic pathways to the energy-producing TCA cycle.Especially, induction of hyperoxia driven anaplerosis in neurovascular tissues such as the retina during early stages of development could deplete biosynthetic precursors from newly proliferating endothelial cells impeding physio

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A study of Ozizza archaeological and ethnographical sites and features in Ebonyi state of Nigeria: research methodological discussion

Ozizza community is one outstanding heritage site, which straddles the East of Ugwuegu and Ukpa rock shelters and has a total area of 24.32km2.Ozizza is situated on a hill, with undulating plain, and lies between N900E north of Upper Afikpo.It is endowed with both archaeological and ethnographic resources; interestingly, this golden literider gp162

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